Holy orders and novitiate in a Piarist monastery; teaching in a Piarist school at Stràznice, Moravia; 1806 education at the Piarist Philosophical Institute in Litomysl (eastern Bohemia); 1807 abandonment of his ecclesiastical career; philosophical studies in Prague and tutoring to earn his living; after three years at the estate of Blatná as tutor to the son of Baron Hildprandt, studies of medicine at Prague which he finished in 1818; prosector and assistant in anatomy at Prague; 1823 professor of physiology at Breslau; 1839 opening of a modest independent physiological institute in Breslau, the first of its kind; 1850 professor of physiology at Prague; 1853 foundation of the Czech scientific review Ziva and until 1863 editor of the same; 1862 co-founder of the Czech medical organization Spolek lékaru ceskych.